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soyasapogenol B

Names

[ CAS No. ]:
595-15-3

[ Name ]:
soyasapogenol B

[Synonym ]:
soyasapogenin B
21-HYDROXYPREGNENOLONE 3,21-DIACETATE
Soyasapogenol B
(3β,22β)-Olean-12-ene-3,22,24-triol
Olean-12-ene-3,22,24-triol, (3β,22β)-

Biological Activity

[Description]:

Soyasapogenol B, an ingredient of soybean, exerts anti-proliferative, anti-metastatic activities. Soyasapogenol B triggers endoplasmic reticulum stress, which mediates apoptosis and autophagy in colorectal cancer[1][2].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer
Signaling Pathways >> Autophagy >> Autophagy

[References]

[1]. Wang L, et al. Endoplasmic reticulum stress triggered by Soyasapogenol B promotes apoptosis and autophagy in colorectal cancer. Life Sci. 2019 Feb 1;218:16-24.

[2]. Wang L, et al. Soyasapogenol B exhibits anti-growth and anti-metastatic activities in clear cell renal cell carcinoma. Naunyn Schmiedebergs Arch Pharmacol. 2019 May;392(5):551-563.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
555.5±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C30H50O3

[ Molecular Weight ]:
458.716

[ Flash Point ]:
226.6±24.7 °C

[ Exact Mass ]:
458.376007

[ PSA ]:
60.69000

[ LogP ]:
7.41

[ Vapour Pressure ]:
0.0±3.4 mmHg at 25°C

[ Index of Refraction ]:
1.562

Safety Information

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

Related Compounds