20α,22R-Dihydroxycholesterol

Names

[ CAS No. ]:
596-94-1

[ Name ]:
20α,22R-Dihydroxycholesterol

[Synonym ]:
20α,22R-Dihydroxycholesterol
(22R)-20α,22-Dihydroxycholesterol
Cholest-5-ene-3,20,22-triol, (3β,22R)-
Oxy-16
20,22-dihydroxycholesterol
(3β,22R)-Cholest-5-ene-3,20,22-triol
(20R,22R)-20,22-Dihydroxycholesterol

Biological Activity

[Description]:

20α,22R-Dihydroxycholesterol is an endogenous metabolic intermediate. 20α,22R-Dihydroxycholesterol involved in the biosynthesis of cholesterol to steroid hormones[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. Mast N, et, al. Structural basis for three-step sequential catalysis by the cholesterol side chain cleavage enzyme CYP11A1. J Biol Chem. 2011 Feb 18;286(7):5607-13.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
553.5±25.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₇H₄₆O₃

[ Molecular Weight ]:
418.652

[ Flash Point ]:
233.1±17.8 °C

[ Exact Mass ]:
418.344696

[ PSA ]:
60.69000

[ LogP ]:
5.98

[ Vapour Pressure ]:
0.0±3.4 mmHg at 25°C

[ Index of Refraction ]:
1.550

20α,22R-Dihydroxycholesterol

Names

Biological Activity

Chemical & Physical Properties

Related Compounds