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2,3-dihydroxypropanoic acid

Names

[ CAS No. ]:
6000-40-4

[ Name ]:
2,3-dihydroxypropanoic acid

[Synonym ]:
Propanoic acid, 2,3-dihydroxy-, (2R)-
EINECS 207-472-9
D-(+)-Glyceric acid
(2R)-2,3-Dihydroxypropanoic acid
(R)-GLYCERIC ACID
19D9ZZX4MH
Glyceric acid
R-glyceric acid
D-glyceric acid

Biological Activity

[Description]:

D-Glyceric acid is an endogenous metabolite present in Urine that can be used for the research of Primary hyperoxaluria Type I and Glutaric Acidemia Type 2[1][2][3].

[Related Catalog]:

Research Areas >> Metabolic Disease

[In Vitro]

Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].

[References]

[1]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720.  

[2]. Dietzen DJ, et al. Extraction of glyceric and glycolic acids from urine with tetrahydrofuran: utility in detection of primary hyperoxaluria. Clin Chem. 1997 Aug;43(8 Pt 1):1315-20.  

[3]. Chlebeck PT, et al. Long-term prognosis in primary hyperoxaluria type II (L-glyceric aciduria). Am J Kidney Dis. 1994 Feb;23(2):255-9.  

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
412.0±30.0 °C at 760 mmHg

[ Molecular Formula ]:
C3H6O4

[ Molecular Weight ]:
106.077

[ Flash Point ]:
217.1±21.1 °C

[ Exact Mass ]:
106.026611

[ LogP ]:
-1.92

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.515

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds