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alpha-(Aminomethyl)-2,5-dimethoxybenzyl alcohol hydrochloride

Names

[ CAS No. ]:
60407-53-6

[ Name ]:
alpha-(Aminomethyl)-2,5-dimethoxybenzyl alcohol hydrochloride

[Synonym ]:
1-(2,5-dimethoxyphenyl)-2-aminoethanol hydrochloride
2-Amino-1-(2,5-dimethoxy-phenyl)-aethanol,Hydrochlorid
2-amino-1-(2,5-dimethoxy-phenyl)-ethanol,hydrochloride
2-azanyl-1-(2,5-dimethoxyphenyl)ethanol hydrochloride

Chemical & Physical Properties

[ Boiling Point ]:
364.3ºC at 760 mmHg

[ Melting Point ]:
158.5ºC

[ Molecular Formula ]:
C10H16ClNO3

[ Molecular Weight ]:
233.69200

[ Flash Point ]:
174.1ºC

[ Exact Mass ]:
233.08200

[ PSA ]:
64.71000

[ LogP ]:
2.19820

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DN6825000
CHEMICAL NAME :
Benzyl alcohol, alpha-aminomethyl-2,5-dimethoxy-, hydrochloride
CAS REGISTRY NUMBER :
60407-53-6
LAST UPDATED :
199303
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C10-H15-N-O3.Cl-H
MOLECULAR WEIGHT :
233.72
WISWESSER LINE NOTATION :
Z1YQR BO1 EO1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1470 ug/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Behavioral - convulsions or effect on seizure threshold Skin and Appendages - hair
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 21,529,1987
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
131 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - somnolence (general depressed activity) Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 92,283,1948
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3770 ug/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Behavioral - convulsions or effect on seizure threshold Behavioral - stiffness
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 21,529,1987

Synthetic Route


Related Compounds