(R)-(1-Aminoethyl)phosphonic acid
Names
[ CAS No. ]:
60687-36-7
[ Name ]:
(R)-(1-Aminoethyl)phosphonic acid
[Synonym ]:
10-hydroxycamphor
(R)-(-)-1-AMINOETHYL-PHOSPHONIC ACID
D-11-Hydroxy-campher
MFCD00066502
Chemical & Physical Properties
[ Density]:
1.475 g/cm3
[ Boiling Point ]:
319.2ºC at 760 mmHg
[ Melting Point ]:
290ºC (dec.)(lit.)
[ Molecular Formula ]:
C2H8NO3P
[ Molecular Weight ]:
125.06400
[ Flash Point ]:
146.9ºC
[ Exact Mass ]:
125.02400
[ PSA ]:
93.36000
[ LogP ]:
0.16910
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
26-36
[ RIDADR ]:
UN 3261
[ HS Code ]:
2931900090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2931900090
[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%
Articles
Nature 272 , 56, (1978)
Synthesis and structure-activity relationships of antibacterial phosphonopeptides incorporating (1-aminoethyl)phosphonic acid and (aminomethyl)phosphonic acid.
J. Med. Chem. 29 , 29, (1986)
Phosphonodipeptides and phosphonooligopeptides based on L- and D-(1-aminoethyl)phosphonic acids L-Ala(P) and D-Ala(P) and (aminomethyl)phosphonic acid Gly(P) at the acid terminus have been synthesized...
Phosphonopeptides as antibacterial agents: rationale, chemistry, and structure-activity relationships.Antimicrob. Agents Chemother. 15 , 677, (1979)
Peptide mimetics with C-terminal residues simulating natural amino acids have been designed as inhibitors of bacterial cell wall biosynthesis. The phosphonopeptide series consisting of various l and d...