DIGOXIGENIN-3,12-DIACETATE
Names
[ CAS No. ]:
6078-59-7
[ Name ]:
DIGOXIGENIN-3,12-DIACETATE
[Synonym ]:
digitoxigenin
[(3S,5R,10S,12R,13S,14S,17R)-12-acetyloxy-14-hydroxy-10,13-dimethyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl] acetate
Digoxigenin diacetate
Diacetyldigoxigenin
3,12-Diacetyl-digoxingenin
3,12-Diacetyldigoxigenin
Chemical & Physical Properties
[ Density]:
1.24g/cm3
[ Boiling Point ]:
589.2ºC at 760 mmHg
[ Melting Point ]:
223ºC
[ Molecular Formula ]:
C27H38O7
[ Molecular Weight ]:
474.58600
[ Flash Point ]:
190.9ºC
[ Exact Mass ]:
474.26200
[ PSA ]:
99.13000
[ LogP ]:
3.71670
[ Index of Refraction ]:
1.562
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- FH5415000
- CHEMICAL NAME :
- 5-beta-Card-20(22)-enolide, 3-beta,12-beta,14-trihydroxy-, 3,12-diacetate
- CAS REGISTRY NUMBER :
- 6078-59-7
- LAST UPDATED :
- 198806
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C27-H38-O7
- MOLECULAR WEIGHT :
- 474.65
- WISWESSER LINE NOTATION :
- L E5 B666TJ A1 E1 DOV1 IQ OOV1 F- DT5OV EHJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 4790 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 18,311,1962
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 20200 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 18,311,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Bird - pigeon
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 8,18,1960
Safety Information
[ RIDADR ]:
UN 2811
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)