5'-Adenylic acid

Names

[ CAS No. ]:
61-19-8

[ Name ]:
5'-Adenylic acid

[Synonym ]:
a-5mp
5'-AMP
phosphate d'adénosine
adenovite
ADENOSINE-5'-MONOPHOSPHORIC ACID
[(2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxytetrahydro-2-furanyl]methyl dihydrogen phosphate
EINECS 200-500-0
Adenosine-5'-monophosphate
myoston
MFCD00005750
t-Adenylic Acid
adenosine phosphate
5'-Adenylic acid
phosphate d'adenosine
phosaden
AMP
adenosine-5′-monophosphate
adenyl
Ado-5'-P
adenosine 5′-monophosphate
my-b-den
Adenosine-5'-phosphoric Acid
Adenosine 5'-monophosphate
Adenosine 5'-phosphoric acid
lycedan
Adenosine monophosphate

Biological Activity

[Description]:

Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.

[Related Catalog]:

Natural Products >> Others

Research Areas >> Others

[Target]

Human Endogenous Metabolite

[In Vitro]

Adenosine monophosphate is a product of various enzymatic reactions, many of which are dysregulated during disease conditions[1].

[References]

[1]. Mondal S, et al. Utility of Adenosine Monophosphate Detection System for Monitoring the Activities of Diverse Enzyme Reactions. Assay Drug Dev Technol. 2017 Oct/Nov;15(7):330-341.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
2.3±0.1 g/cm3

[ Boiling Point ]:
798.5±70.0 °C at 760 mmHg

[ Melting Point ]:
178-185 °C

[ Molecular Formula ]:
C₁₀H₁₄N₅O₇P

[ Molecular Weight ]:
347.221

[ Flash Point ]:
436.7±35.7 °C

[ Exact Mass ]:
347.063080

[ PSA ]:
195.88000

[ LogP ]:
-0.22

[ Vapour Pressure ]:
0.0±3.0 mmHg at 25°C

[ Index of Refraction ]:
1.905

[ Water Solubility ]:
H2O: with addition of mild alkalisoluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AU7480500

CHEMICAL NAME :: 5'-Adenylic acid

CAS REGISTRY NUMBER :: 61-19-8

BEILSTEIN REFERENCE NO. :: 0054612

LAST UPDATED :: 199701

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C10-H14-N5-O7-P

MOLECULAR WEIGHT :: 347.26

WISWESSER LINE NOTATION :: T56 BN DN FN HNJ IZ D- BT5OTJ CQ DQ E1OPQQO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 2800 mg/kg

SEX/DURATION :: female 7-13 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 2800 mg/kg

SEX/DURATION :: female 7-13 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Rodent - mouse Cells - not otherwise specified

DOSE/DURATION :: 50 umol/L

REFERENCE :: JIDEAE Journal of Investigative Dermatology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1938- Volume(issue)/page/year: 66,313,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3805 No. of Facilities: 973 (estimated) No. of Industries: 2 No. of Occupations: 9 No. of Employees: 12179 (estimated) No. of Female Employees: 8315 (estimated)

Safety Information

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
AU7480500

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%