Flumezapine
Names
[ CAS No. ]:
61325-80-2
[ Name ]:
Flumezapine
[Synonym ]:
Flumezapinum [INN-Latin]
Flumezapine (USAN)
Flumezapinum
10H-Thieno(2,3-b)(1,5)benzodiazepine,7-fluoro-2-methyl-4-(4-methyl-1-piperazinyl)
Flumezapina [INN-Spanish]
7-fluoro-2-methyl-4-(4-methyl-piperazin-1-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepine
Flumezapina
FLUMEZAPINE
7-Fluoro-2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno(2,3-b)(1,5)benzodiazepine
Chemical & Physical Properties
[ Density]:
1.383g/cm3
[ Boiling Point ]:
479.498ºC at 760 mmHg
[ Molecular Formula ]:
C17H19FN4S
[ Molecular Weight ]:
330.42300
[ Flash Point ]:
243.792ºC
[ Exact Mass ]:
330.13100
[ PSA ]:
59.11000
[ LogP ]:
3.02770
[ Index of Refraction ]:
1.697
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XJ9007100
- CHEMICAL NAME :
- 10H-Thieno(2,3-b)(1,5)benzodiazepine, 7-fluoro-2-methyl-4-(4-methyl-1-piperazinyl)-
- CAS REGISTRY NUMBER :
- 61325-80-2
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C17-H19-F-N4-S
- MOLECULAR WEIGHT :
- 330.46
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - body temperature decrease
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,878,1980