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methyl piperate

Names

[ CAS No. ]:
6190-46-1

[ Name ]:
methyl piperate

Biological Activity

[Description]:

Methylpiperic acid is a piperine alkaloid with significant MAO inhibitory activity (IC503.6 μM). Methylpiperic acid is less effective against MAO-B (IC 501.6 μM) than MAO-A (IC5027.1 μM) has a bidirectional inhibitory effect. Methylphenidate is used to treat mental disorders [1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase
Research Areas >> Neurological Disease

[Target]

MAO-B


[References]

[1]. Lee SA, et al. Methylpiperate derivatives from Piper longum and their inhibition of monoamine oxidase. Arch Pharm Res. 2008 Jun;31(6):679-83.  

Chemical & Physical Properties

[ Molecular Formula ]:
C13H12O4

[ Molecular Weight ]:
232.23

[ Exact Mass ]:
232.07400

[ PSA ]:
44.76000

[ LogP ]:
2.15770

Precursor & DownStream

Precursor

DownStream


Related Compounds