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trans-permethrin

Names

[ CAS No. ]:
61949-77-7

[ Name ]:
trans-permethrin

[Synonym ]:
EINECS 263-347-9
MFCD00145431
trans-Permethrin solution

Biological Activity

Chemical & Physical Properties

[ Density]:
1.293g/cm3

[ Boiling Point ]:
465.9ºC at 760 mmHg

[ Molecular Formula ]:
C21H20Cl2O3

[ Molecular Weight ]:
391.28800

[ Flash Point ]:
-18ºC

[ Exact Mass ]:
390.07900

[ PSA ]:
35.53000

[ LogP ]:
6.11330

[ Index of Refraction ]:
1.615

[ Storage condition ]:
APPROX 4°C

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GZ1251580
CHEMICAL NAME :
Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, (3-phenoxyphenyl) methyl ester, trans-
CAS REGISTRY NUMBER :
61949-77-7
LAST UPDATED :
199510
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C21-H20-Cl2-O3
MOLECULAR WEIGHT :
391.31

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>800 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - tremor
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 66,153,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>135 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - tremor
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 66,153,1982 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,329,1991 IARC Cancer Review:Human No Available Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,329,1991 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 53,329,1991

Safety Information

[ Symbol ]:

GHS02, GHS07, GHS08, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H304-H315-H336-H410

[ Precautionary Statements ]:
P210-P261-P273-P301 + P310-P331-P501

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F,Xn,N

[ Risk Phrases ]:
11-38-50/53-65-67

[ Safety Phrases ]:
S60;S61;S62

[ RIDADR ]:
UN 1145 3/PG 2

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J. Med. Entomol. 50(4) , 826-32, (2013)

ABSTRACT Phytochemicals have been considered as alternatives for conventional pesticides because of their low mammalian toxicity and environmental safety. They usually display less potent insecticidal...

Field-collected permethrin-resistant Aedes aegypti from central Thailand contain point mutations in the domain IIS6 of the sodium channel gene (KDR).

Southeast Asian J. Trop. Med. Public Health 43(6) , 1380-6, (2012)

One of the mechanisms responsible for pyrethroid resistance in mosquitoes is mutations in domain IIS6 of voltage-gated sodium channel gene (kdr). Aedes aegypti larvae were collected from the central p...

Efficacy of three insecticides against Anopheles dirus and Anopheles minimus, the major malaria vectors, in Kanchanaburi Province, Thailand.

Southeast Asian J. Trop. Med. Public Health 43(6) , 1339-45, (2012)

We conducted this study to determine the insecticide susceptibility of two malaria vectors, Anopheles dirus and Anopheles minimus from Kanchanaburi Province, Thailand. The mosquitoes were collected an...


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