N-alpha-Acetyl-L-ornithine

Names

[ Name ]:
N-alpha-Acetyl-L-ornithine

[Synonym ]:
N(2)-acetyl-L-ornithine
N-acetylornithine
ACETYL-L-ORNITHINE
Ornithine,N2-acetyl
AOR
(2S)-2-acetamido-5-aminopentanoic acid
N|A-Acetyl-L-ornithine
N-α-acetyl-l-ornithine
N-alpha-Acetyl-L-ornithine

Biological Activity

[Description]:

N-Acetylornithine is an intermediate in the enzymatic biosynthesis of the amino acid L-arginine from L-glutamate.

[Related Catalog]:

Natural Products >> Others

Research Areas >> Others

[Target]

Human Endogenous Metabolite

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.171g/cm3

[ Boiling Point ]:
436.2ºC at 760 mmHg

[ Molecular Formula ]:
C₇H₁₄N₂O₃

[ Molecular Weight ]:
174.19800

[ Flash Point ]:
217.6ºC

[ Exact Mass ]:
174.10000

[ PSA ]:
92.42000

[ LogP ]:
0.40580

[ Appearance of Characters ]:
Solid

[ Index of Refraction ]:
1.492

[ Storage condition ]:
−20°C

[ Water Solubility ]:
Freely soluble (880 g/L) (25 ºC)

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924199090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Metabolomic profiling of serum in the progression of Alzheimer's disease by capillary electrophoresis-mass spectrometry.

Electrophoresis 35(23) , 3321-30, (2014)

There is high interest in the discovery of early diagnostic biomarkers of Alzheimer's disease, for which metabolomics exhibits a great potential. In this work, a metabolomic approach based on ultrafil...

Inhibitors of N(alpha)-acetyl-L-ornithine deacetylase: synthesis, characterization and analysis of their inhibitory potency.

Amino Acids 38 , 1155-1164, (2010)

A series of N (alpha)-acyl (alkyl)- and N (alpha)-alkoxycarbonyl-derivatives of L- and D-ornithine were prepared, characterized, and analyzed for their potency toward the bacterial enzyme N (alpha)-ac...

Model-driven discovery of underground metabolic functions in Escherichia coli.

Proc. Natl. Acad. Sci. U. S. A. 112(3) , 929-34, (2015)

Enzyme promiscuity toward substrates has been discussed in evolutionary terms as providing the flexibility to adapt to novel environments. In the present work, we describe an approach toward exploring...