3-(m-Tolyloxy)-1,2-propanediol
Names
[ CAS No. ]:
621-24-9
[ Name ]:
3-(m-Tolyloxy)-1,2-propanediol
[Synonym ]:
3-m-Tolyloxy-propan-1,2-diol
3-m-tolyloxy-propane-1,2-diol
m-Mephenesin
Chemical & Physical Properties
[ Density]:
1.152g/cm3
[ Boiling Point ]:
354.7ºC at 760 mmHg
[ Molecular Formula ]:
C10H14O3
[ Molecular Weight ]:
182.21600
[ Flash Point ]:
168.3ºC
[ Exact Mass ]:
182.09400
[ PSA ]:
49.69000
[ LogP ]:
0.72700
[ Index of Refraction ]:
1.545
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TZ1200000
- CHEMICAL NAME :
- 1,2-Propanediol, 3-(m-tolyloxy)-
- CAS REGISTRY NUMBER :
- 621-24-9
- BEILSTEIN REFERENCE NO. :
- 1948930
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C10-H14-O3
- MOLECULAR WEIGHT :
- 182.24
- WISWESSER LINE NOTATION :
- Q1YQ1OR C1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 700 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 72,1545,1952
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1474 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - muscle weakness Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 93,470,1948