3-nitro-L-tyrosine

Names

[ CAS No. ]:
621-44-3

[ Name ]:
3-nitro-L-tyrosine

[Synonym ]:
L-3-NO2-Tyr
H-3-NITRO-TYR-OH
M-NITRO-L-TYROSINE
Tyrosine, 3-nitro-, L- (8CI)
EINECS 210-688-6
3-Nitro-Tyrosine
L-Tyrosine, 3-nitro-
Tyrosine, 3-nitro-
Tyrosine, 3-nitro-, L-
3-Nitro-L-tyrosine
3-Nitrotyrosine
Nitrotyrosine
L-4-hydroxy-3-nitro-phenylalanine
H-3-NITRO-L-TYROSINE
MFCD00007123
H-M-NITRO-TYR-OH
H-Tyr(3-NO2)-OH

Biological Activity

[Description]:

3-Nitro-L-tyrosine is a biomarker of nitrogen free radical species modified proteins in systemic autoimmunogenic conditions.

[Related Catalog]:

Research Areas >> Metabolic Disease

Natural Products >> Others

[Target]

Human Endogenous Metabolite

[References]

[1]. Montoliu C, et al. 3-nitro-tyrosine as a peripheral biomarker of minimal hepatic encephalopathy in patients with liver cirrhosis. Am J Gastroenterol. 2011 Sep;106(9):1629-37.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
431.6±45.0 °C at 760 mmHg

[ Melting Point ]:
233-235ºC (dec.)

[ Molecular Formula ]:
C₉H₁₀N₂O₅

[ Molecular Weight ]:
226.186

[ Flash Point ]:
214.8±28.7 °C

[ Exact Mass ]:
226.058975

[ PSA ]:
129.37000

[ LogP ]:
0.60

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.651

[ Storage condition ]:
2~8℃

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922509090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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