2-Nitroethanol

Names

[ CAS No. ]:
625-48-9

[ Name ]:
2-Nitroethanol

[Synonym ]:
1-nitro-2-ethanol
2-hydroxy-1-nitroethane
Ethanol,2-nitro
2-nitro-1-ethanol
2-Nitroethanol
β-Nitroethanol
EINECS 210-895-1
2-Nitro-ethanol
MFCD00007405
2-nitroethan-1-ol
Ethanol, 2-nitro-
2-hydroxynitroethane
nitroethanol

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
193.8±0.0 °C at 760 mmHg

[ Melting Point ]:
−80 °C(lit.)

[ Molecular Formula ]:
C₂H₅NO₃

[ Molecular Weight ]:
91.066

[ Flash Point ]:
113.8±11.1 °C

[ Exact Mass ]:
91.026939

[ PSA ]:
66.05000

[ LogP ]:
-0.42

[ Vapour Pressure ]:
0.1±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.438

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KL9370000

CHEMICAL NAME :: Ethanol, 2-nitro-

CAS REGISTRY NUMBER :: 625-48-9

BEILSTEIN REFERENCE NO. :: 1633753

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C2-H5-N-O3

MOLECULAR WEIGHT :: 91.08

WISWESSER LINE NOTATION :: WN2Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 1 mg/plate

REFERENCE :: EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 19(Suppl 21),2,1992

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
KL9370000

[ HS Code ]:
29055910

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2905590090

[ Summary ]:
2905590090 other halogenated, sulphonated, nitrated or nitrosated derivatives of acyclic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Pharmacologic alternatives to riboflavin photochemical corneal cross-linking: a comparison study of cell toxicity thresholds.

Invest. Ophthalmol. Vis. Sci. 55(5) , 3247-57, (2014)

The efficacy of therapeutic cross-linking of the cornea using riboflavin photochemistry (commonly abbreviated as CXL) has caused its use to become widespread. Because there are known chemical agents t...

Effects of select nitrocompounds on in vitro ruminal fermentation during conditions of limiting or excess added reductant.

Bioresour. Technol. 99(18) , 8655-61, (2008)

Ruminal methane (CH(4)) production results in the loss of up to 12% of gross energy intake and contributes nearly 20% of the United States' annual emission of this greenhouse gas. We report the effect...

Aliphatic beta-nitro alcohols for non-enzymatic collagen cross-linking of scleral tissue.

Exp. Eye Res. 87(3) , 279-85, (2008)

The success of riboflavin photochemical cross-linking of the cornea in treating keratoconus and post-surgical keratectasia has prompted interest in cross-linking scleral tissue with a potential applic...