1-Chloro-2-naphthol
Names
[ CAS No. ]:
633-99-8
[ Name ]:
1-Chloro-2-naphthol
[Synonym ]:
chloro-2-naphthol
1-chloro-2-naphthol
2-Naphthalenol,1-chloro
2-NAPHTHOL,1-CHLORO
1-Chloro-2-Naphthalenol
1-chloro-naphthalen-2-ol
1-chloronaphthalene-2-ol
1-chloro-2-naphtol
1-Chloro-2-hydroxynaphthalene
Chemical & Physical Properties
[ Density]:
1.333g/cm3
[ Boiling Point ]:
306.5ºC at 760 mmHg
[ Melting Point ]:
70ºC
[ Molecular Formula ]:
C10H7ClO
[ Molecular Weight ]:
178.61500
[ Flash Point ]:
139.2ºC
[ Exact Mass ]:
178.01900
[ PSA ]:
20.23000
[ LogP ]:
3.19880
[ Index of Refraction ]:
1.684
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QL3410000
- CHEMICAL NAME :
- 2-Naphthol, 1-chloro-
- CAS REGISTRY NUMBER :
- 633-99-8
- BEILSTEIN REFERENCE NO. :
- 1939233
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C10-H7-Cl-O
- MOLECULAR WEIGHT :
- 178.62
- WISWESSER LINE NOTATION :
- L66J BG CQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2310 mg/kg
- TOXIC EFFECTS :
- Behavioral - withdrawal Gastrointestinal - changes in structure or function of salivary glands
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 32(4),55,1988
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 580 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 32(4),55,1988
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 275 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- IJPAAO Indian Journal of Pharmacy. (Bombay, India) V.1-40(1), 1939-78. For publisher information, see IJSIDW. Volume(issue)/page/year: 30,89,1968