Adrafinil

Names

[ Name ]:
Adrafinil

[Synonym ]:
[2-(diphenyl)methanesulfinyl]-N-hydroxy-acetamide
EINECS 264-303-1
2-benzhydrylsulfinyl-N-hydroxyacetamide
Olmifon
benzhydrylsulphinyl-acetohydroxamic acid
2-(Benzhydrylsulfinyl)acetohydroxamic acid
2-[(Diphenylmethyl)sulfinyl]-N-hydroxyacetamide
Acetamide, 2-[(diphenylmethyl)sulfinyl]-N-hydroxy-
Adrafinil
Acetamide,2-((diphenylmethyl)sulfinyl)-N-hydroxy
MFCD00865357
2-[(Diphenylmethyl)sulfinyl]acetohydroxamic acid
2-(benzhydrylsulphinyl)acetohydroxamic acid

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Melting Point ]:
159-1600C

[ Molecular Formula ]:
C₁₅H₁₅NO₃S

[ Molecular Weight ]:
289.349

[ Exact Mass ]:
289.077271

[ PSA ]:
85.61000

[ LogP ]:
0.77

[ Index of Refraction ]:
1.653

[ Storage condition ]:
-20°C Freezer

[ Water Solubility ]:
DMSO: 35 mg/mL

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AB8139500

CHEMICAL NAME :: Acetamide, 2-((diphenylmethyl)sulfinyl)-N-hydroxy-

CAS REGISTRY NUMBER :: 63547-13-7

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C15-H15-N-O3-S

MOLECULAR WEIGHT :: 289.37

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1950 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4066686

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 859 mg/kg

TOXIC EFFECTS :: Behavioral - excitement

REFERENCE :: JNPHAG Journal de Pharmacologie. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1970- Volume(issue)/page/year: 17,37,1986

Safety Information

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R22

[ WGK Germany ]:
3

[ RTECS ]:
AB8139500

[ HS Code ]:
2942000000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%