3-Phenylpropiolic acid
Names
[ CAS No. ]:
637-44-5
[ Name ]:
3-Phenylpropiolic acid
[Synonym ]:
MFCD00004361
2-Propynoic acid, 3-phenyl-
β-phenylpropargylic acid
3-Phenyl-2-propynoic acid
3-phenyl-propiolic acid
phenylpropiolic acid
b-phenylpropargylic acid
EINECS 211-285-8
3-Phenylprop-2-ynoic acid
phenyl-propiolic acid
Biological Activity
[Description]:
[Related Catalog]:
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
302.6±15.0 °C at 760 mmHg
[ Melting Point ]:
135-137 °C(lit.)
[ Molecular Formula ]:
C9H6O2
[ Molecular Weight ]:
146.143
[ Flash Point ]:
151.0±16.9 °C
[ Exact Mass ]:
146.036774
[ PSA ]:
37.30000
[ LogP ]:
2.61
[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C
[ Index of Refraction ]:
1.603
[ Storage condition ]:
0-6°C
[ Water Solubility ]:
freely soluble
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
29163900
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2916399090
[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Proc. Natl. Acad. Sci. U. S. A. 110(24) , 9728-33, (2013)
The branched-chain amino acids (BCAAs) leucine, isoleucine, and valine are elevated in maple syrup urine disease, heart failure, obesity, and type 2 diabetes. BCAA homeostasis is controlled by the mit...
Carbon isotope fractionation in the decarboxylation of phenylpropiolic acid in hydrogen donating media.Isotopes Environ. Health Stud. 37(3) , 239-52, (2001)
13C kinetic isotope effect (KIE) in the decarboxylation of phenylpropiolic acid (PPA) in tetralin medium (Tn) has been determined at 409-432 K and found to be of magnitude similar to the 13C KIE obser...
Inactivation of peptidylglycine α-hydroxylating monooxygenase by cinnamic acid analogs.J. Enzyme Inhib. Med. Chem. 31 , 551-62, (2016)
Peptidylglycine α-amidating monooxygenase (PAM) is a bifunctional enzyme that catalyzes the final reaction in the maturation of α-amidated peptide hormones. Peptidylglycine α-hydroxylating monooxygena...