etbe

Names

[ CAS No. ]:
637-92-3

[ Name ]:
etbe

[Synonym ]:
tert-Butyl ethyl ether
EINECS 211-309-7
2-Ethoxy-2-methylpropane
t-butyl ethyl ether
Propane, 2-ethoxy-2-methyl-
etbe
MFCD00009225

Chemical & Physical Properties

[ Density]:
0.8±0.1 g/cm3

[ Boiling Point ]:
70.0±0.0 °C at 760 mmHg

[ Melting Point ]:
−97 °C(lit.)

[ Molecular Formula ]:
C₆H₁₄O

[ Molecular Weight ]:
102.175

[ Flash Point ]:
-19.4±0.0 °C

[ Exact Mass ]:
102.104462

[ PSA ]:
9.23000

[ LogP ]:
1.68

[ Vapour Pressure ]:
142.6±0.1 mmHg at 25°C

[ Index of Refraction ]:
1.387

[ Storage condition ]:
Flammables area

[ Stability ]:
Stable, but may react with air to form peroxides. Once opened, store under an inert atmosphere and test for the presence of peroxides before use. Highly flammable. Incompatible with strong oxidizing agents.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KN4730200

CHEMICAL NAME :: Ether, tert-butyl ethyl

CAS REGISTRY NUMBER :: 637-92-3

LAST UPDATED :: 199806

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C6-H14-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 123 gm/m3/15M

TOXIC EFFECTS :: Behavioral - general anesthetic

REFERENCE :: ANESAV Anesthesiology. (Lippincott/Harper, Journal Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1940- Volume(issue)/page/year: 11,455,1950 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5000 ppm/6H/13W-I

TOXIC EFFECTS :: Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Endocrine - changes in adrenal weight

REFERENCE :: TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 36(1,pt2),340,1997

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5000 ppm/6H/13W-I

TOXIC EFFECTS :: Liver - other changes Liver - changes in liver weight

REFERENCE :: TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 36(1,pt2),340,1997

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H336

[ Precautionary Statements ]:
P210-P261

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F: Flammable;Xi: Irritant;

[ Risk Phrases ]:
R11

[ Safety Phrases ]:
S16-S26

[ RIDADR ]:
UN 1179 3/PG 2

[ WGK Germany ]:
1

[ RTECS ]:
KN4730200

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
2909199090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2909199090

[ Summary ]:
2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

Oxidative degradation of alternative gasoline oxygenates in aqueous solution by ultrasonic irradiation: Mechanistic study

Sci. Total Environ. 430 , 246-59, (2012)

Widespread pollution has been associated with gasoline oxygenates of branched ethers methyl tert-butyl ether (MTBE), di-isopropyl ether (DIPE), ethyl tert-butyl ether (ETBE), and tert-amyl ether (TAME...

Aldh2 knockout mice were more sensitive to DNA damage in leukocytes due to ethyl tertiary butyl ether exposure.

Ind. Health 49(3) , 396-9, (2011)

To clarify the genotoxicity of ethyl tertiary butyl ether (ETBE), a gasoline additive, male and female C57BL/6 mice of Aldh2+/+ and Aldh2-/- genotypes, aged 8 wk, were exposed to 0, 500, 1,750, or 5,0...

ETBE (ethyl tert butyl ether) and TAME (tert amyl methyl ether) affect microbial community structure and function in soils.

J. Hazard. Mater. 187(1-3) , 488-94, (2011)

Ethyl tert butyl ether (ETBE) and tert amyl methyl ether (TAME) are oxygenates used in gasoline in order to reduce emissions from vehicles. The present study investigated their impact on a soil microf...