Ocrelizumab
Names
[ CAS No. ]:
637334-45-3
[ Name ]:
Ocrelizumab
[Synonym ]:
Monoclonal antibody Pro70769
Pro-70769
Pro70769
Rhumab 2H7
Biological Activity
[Description]:
Ocrelizumab is an anti-CD20 antibody that depletes circulating immature and mature B cells but spares CD20-negative plasma cells. The effector mechanisms of Ocrelizumab are complement-dependent cytotoxicity and antibody-dependent cellular cytotoxicity. Ocrelizumab is the first monoclonal antibody for secondary primary progressive multiple sclerosis (PPMS)[1].
[Related Catalog]:
[References]
Chemical & Physical Properties
No Any Chemical & Physical Properties