Spectinomycin sulfate tetrahydrate
Names
[ CAS No. ]:
64058-48-6
[ Name ]:
Spectinomycin sulfate tetrahydrate
[Synonym ]:
SPECTINOMYCIN SULPHATE
Trobicin sulfate
(2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-4a,7,9-Trihydroxy-2-methyl-6,8-bis(methylamino)decahydro-4H-pyrano[2,3-b][1,4]benzodioxin-4-one sulfate hydrate (1:1:1)
SpectinoMycin sulfate tetrahydrate CGMP/FDA
SPECTINOMYCINHCL
Actinospectacin,tetrahydrate,sulfate
Spectinomycin sulfate
4H-Pyrano[2,3-b][1,4]benzodioxin-4-one, decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-, sulfate, hydrate (1:1:1) (salt)
Spectinomycin,tetrahydrate,sulfate
Chemical & Physical Properties
[ Boiling Point ]:
583.1ºC at 760 mmHg
[ Melting Point ]:
~185° (dec)
[ Molecular Formula ]:
C14H34N2O14S
[ Molecular Weight ]:
448.443
[ Exact Mass ]:
448.136292
[ PSA ]:
229.18000
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WG7430000
- CHEMICAL NAME :
- Spectinomycin, sulfate, tetrahydrate
- CAS REGISTRY NUMBER :
- 64058-48-6
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C14-H24-N2-O7.O4-S.4H2-O
- MOLECULAR WEIGHT :
- 500.54
- WISWESSER LINE NOTATION :
- T C666 BO DO GV IOTJ E1 HQ KM1 LQ MM1 NQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- UPJOH* "Compounds Available for Fundamental Research, Volume II-6, Antibiotics, A Program of Upjohn Company Research Laboratory." (Kalamazoo, MI 49001) Volume(issue)/page/year: 2(6),-,1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3867 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- UPJOH* "Compounds Available for Fundamental Research, Volume II-6, Antibiotics, A Program of Upjohn Company Research Laboratory." (Kalamazoo, MI 49001) Volume(issue)/page/year: 2(6),-,1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1022 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- UPJOH* "Compounds Available for Fundamental Research, Volume II-6, Antibiotics, A Program of Upjohn Company Research Laboratory." (Kalamazoo, MI 49001) Volume(issue)/page/year: 2(6),-,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2808 No. of Facilities: 403 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 4029 (estimated) No. of Female Employees: 2015 (estimated)
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302
[ Precautionary Statements ]:
P301 + P312 + P330
[ Hazard Codes ]:
Xn
[ RIDADR ]:
NONH for all modes of transport