5,12-Naphthacenedione,7-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-(hydroxyacetyl)-,hydrochloride, (7S,9S)- (9CI)
Names
[ CAS No. ]:
64363-63-9
[ Name ]:
5,12-Naphthacenedione,7-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-9-(hydroxyacetyl)-,hydrochloride, (7S,9S)- (9CI)
[Synonym ]:
7-Deoxydoxorubicin aglycone
7-deoxyadriamycin aglycone
7-Deoxydoxorubicin aglycon
Doxorubicin 7-deoxyaglycone
7-Deoxy Doxorubicin Aglycone (approxmately)
(+)-4-demethoxyadriamycin hydrochloride
Adriamycin 7-deoxyaglycone
7-Deoxyepirubicin Aglycone
Doxorubicin deoxyaglycone
7-Desoxy-adriamycinon
7-Deoxyadriamycinon
7-DeoxyadriaMycinone
doxorubicin hydrochloride
Chemical & Physical Properties
[ Boiling Point ]:
766.4ºC at 760 mmHg
[ Molecular Formula ]:
C26H27NO10
[ Molecular Weight ]:
513.49300
[ Flash Point ]:
417.3ºC
[ Exact Mass ]:
513.16300
[ PSA ]:
196.84000
[ LogP ]:
0.69300
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QI9329400
- CHEMICAL NAME :
- 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-7-((3-amino-2,3,6-trideoxy-alpha- L-lyxo- hexopyranosyl)oxy)-9-(hydroxyacetyl)-6,9,11-trihydrox y-, (7S-cis)-, hydrochloride
- CAS REGISTRY NUMBER :
- 64363-63-9
- LAST UPDATED :
- 199410
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C26-H27-N-O10.Cl-H
- MOLECULAR WEIGHT :
- 550.00
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 1 ug/plate
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 8,797,1986