FK 33-824

Names

[ Name ]:
FK 33-824

[Synonym ]:
Sandoz 33-824
SAN 33-824
Damme
Tyrosylalanylglycyl-N-[1-hydroxy-4-(methylsulfinyl)-2-butanyl]-Nα-methylphenylalaninamide
FK 33-824
Sandoz FK 33-824
Phenylalaninamide, tyrosylalanylglycyl-N-[1-(hydroxymethyl)-3-(methylsulfinyl)propyl]-Nα-methyl-

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
1033.4±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₉H₄₁N₅O₇S

[ Molecular Weight ]:
603.730

[ Flash Point ]:
578.8±34.3 °C

[ Exact Mass ]:
603.272644

[ PSA ]:
210.37000

[ LogP ]:
-0.82

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.607

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SQ7315350

CHEMICAL NAME :: L-Phenylalaninamide, L-tyrosyl-D-alanylglycyl-N-(1-(hydroxymethyl)-3-(meth ylsulfinyl)propyl)- N(sup alpha)-methyl-, (1S)-

CAS REGISTRY NUMBER :: 64854-64-4

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C29-H41-N5-O7-S

MOLECULAR WEIGHT :: 603.81

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 60 mg/kg

SEX/DURATION :: female 9 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - Central Nervous System

REFERENCE :: TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 31,235,1985

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 65 mg/kg

SEX/DURATION :: female 9 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetal death

REFERENCE :: TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 31,235,1985