3-Hydrazino-5,6,7,8-tetrahydropyrido(4,3-c)pyridazin-6-yl-phenyl-keton
Names
[ CAS No. ]:
65322-72-7
[ Name ]:
3-Hydrazino-5,6,7,8-tetrahydropyrido(4,3-c)pyridazin-6-yl-phenyl-keton
[Synonym ]:
ENDRALAZINE MESYLATE
Endralazine mesilate
BQ 22-708 methanesulfonate
Endralazine methanesulfonate
Chemical & Physical Properties
[ Boiling Point ]:
572.6ºC at 760 mmHg
[ Molecular Formula ]:
C15H19N5O4S
[ Molecular Weight ]:
365.40700
[ Flash Point ]:
300.1ºC
[ Exact Mass ]:
365.11600
[ PSA ]:
146.89000
[ LogP ]:
2.25670
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UV1152450
- CHEMICAL NAME :
- Pyrido(4,3-c)pyridazin-3(2H)-one, 6-benzoyl-5,6,7,8-tetrahydro-, 3-hydrazone, monomethanesulfonate
- CAS REGISTRY NUMBER :
- 65322-72-7
- LAST UPDATED :
- 199410
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C14-H15-N5-O.C-H4-O3-S
- MOLECULAR WEIGHT :
- 365.45
- WISWESSER LINE NOTATION :
- T66 BNNY HN EH&TJ DUNZ HVR &WSQ1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 246 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- DNA damage
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 123 mg/kg
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 4,605,1982