2-(2,4-Difluorophenyl)acetonitrile
Names
[ CAS No. ]:
656-35-9
[ Name ]:
2-(2,4-Difluorophenyl)acetonitrile
[Synonym ]:
EINECS 211-514-1
Benzeneacetonitrile, 2,4-difluoro-
2,4-Difluorophenylacetonitrile
2,4-Difluorobenzyl cyanide
2,4-Difluorobenzeneacetonitrile
NC1R BF DF
(2,4-Difluorophenyl)acetonitrile
MFCD00009971
2-(2,4-difluorophenyl)acetonitrile
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
216.1±25.0 °C at 760 mmHg
[ Molecular Formula ]:
C8H5F2N
[ Molecular Weight ]:
153.129
[ Flash Point ]:
93.3±0.0 °C
[ Exact Mass ]:
153.039001
[ PSA ]:
23.79000
[ LogP ]:
1.59
[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.487
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302 + H312 + H332-H315-H319-H335
[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R20/21/22;R36/37/38
[ Safety Phrases ]:
S26-S36/37
[ RIDADR ]:
3276
[ WGK Germany ]:
3
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
[ HS Code ]:
2926909090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2926909090
[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Bioorg. Med. Chem. 2(5) , 343-55, (1994)
A series of enol HIV-1 protease inhibitors which show competitive inhibition and the structure-activity relationship study which led to the design of these compounds are reported. By systematically mo...