2-(2-Aminothiazole-4-yl)-2-methoxyiminoacetic acid
Names
[ CAS No. ]:
65872-41-5
[ Name ]:
2-(2-Aminothiazole-4-yl)-2-methoxyiminoacetic acid
[Synonym ]:
ThiazoxiMic Acid
4-Thiazoleacetic acid, 2-amino-α-(methoxyimino)-, (αZ)-
(2Z)-(2-Amino-1,3-thiazol-4-yl)(methoxyimino)acetic acid
Aminothiaoximoacid
EINECS 265-957-0
ATIFICIALCOW-BEZOAR
MFCD00071528
Aminothiaoximinoacid
syn-Thiazoximic acid
Cefepime Impurity 4
Chemical & Physical Properties
[ Density]:
1.7±0.1 g/cm3
[ Boiling Point ]:
425.1±37.0 °C at 760 mmHg
[ Melting Point ]:
192 °C (dec.)(lit.)
[ Molecular Formula ]:
C6H7N3O3S
[ Molecular Weight ]:
201.203
[ Flash Point ]:
210.9±26.5 °C
[ Exact Mass ]:
201.020813
[ PSA ]:
126.04000
[ LogP ]:
-0.11
[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C
[ Index of Refraction ]:
1.689
[ Storage condition ]:
-20?C Freezer
[ Water Solubility ]:
0.6 g/100 mL (20 ºC)
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S37/39-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2934100090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934100090
[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%
Articles
Acta Microbiol. Hung. 39(3-4) , 317-22, (1992)
Diazald, a chemical intermediate for the synthesis of biologically active compounds, was found to be a potent in vitro antimicrobial agent against yeasts, yeast-like and filamentous fungi as well as G...
Total Synthesis of Sodium (3S, 4R)-3-[2-(2-Aminothiazol-4-yl)-(Z)-2-methoxyiminoacetamido]-4-methoxymethyl-2-azetidinone-1-sulfonate from D-Aspartic Acid. Chung BY, et al.Bull. Korean Chem. Soc. 13(3) , 315-16, (1992)
Total Synthesis of Sodium (3R, 4S)-3-(2-(2-Aminothiazol-4-yl)-(Z)-2-methoxyiminoacetamido)-4-methoxymethyl-2-azetidinone-1-sulfonate from L-Aspartic Acid. Chung BY, et al.
Bull. Korean Chem. Soc. 13(3) , 311-14, (1992)