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pyridoxal

Names

[ CAS No. ]:
66-72-8

[ Name ]:
pyridoxal

[Synonym ]:
3-hydroxy-2-methyl-5-methylol-isonicotinaldehyde
3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde
3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde
PYRIDOXALDEHYDE
2-Methyl-3-hydroxy-5-(hydroxymethyl)pyridine-4-carbaldehyde
Pyridoxal
3-(Hydroxymethyl)-5-hydroxy-6-methylpyridine-4-carbaldehyde
3-Hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarbaldehyde
PYRIDOXALE
pyridoxal aldehyde

Biological Activity

[Description]:

Pyridoxal is one of the active forms of vitamin B6[1].

[Related Catalog]:

Research Areas >> Cancer

[Target]

Human Endogenous Metabolite


[References]

[1]. Hayashi H. Pyridoxal enzymes: mechanistic diversity and uniformity[J]. The journal of biochemistry, 1995, 118(3): 463-473.

Chemical & Physical Properties

[ Density]:
1.36 g/cm3

[ Boiling Point ]:
412.8ºC at 760 mmHg

[ Molecular Formula ]:
C8H9NO3

[ Molecular Weight ]:
167.16200

[ Exact Mass ]:
167.05800

[ PSA ]:
70.42000

[ LogP ]:
0.40040

[ Index of Refraction ]:
1.639

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UV1200600
CHEMICAL NAME :
Pyridoxal
CAS REGISTRY NUMBER :
66-72-8
BEILSTEIN REFERENCE NO. :
0383768
LAST UPDATED :
199709
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C8-H9-N-O3
MOLECULAR WEIGHT :
167.18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
540 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - rigidity (including catalepsy) Behavioral - irritability
REFERENCE :
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 25,539,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1120 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - rigidity (including catalepsy) Behavioral - irritability
REFERENCE :
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 25,539,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
480 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - rigidity (including catalepsy) Behavioral - irritability
REFERENCE :
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 25,539,1970 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9714 No. of Facilities: 3 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 522 (estimated) No. of Female Employees: 261 (estimated)

Precursor & DownStream


Related Compounds