4-Methylthiosemicarbazide

Names

[ Name ]:
4-Methylthiosemicarbazide

[Synonym ]:
N-Methylhydrazinecarbothioamide
1-amino-3-methylthiourea
MFCD00007617
N-methyl-thiosemicarbazide
EINECS 229-563-2
Hydrazinecarbothioamide, N-methyl-

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
168.4±23.0 °C at 760 mmHg

[ Melting Point ]:
135-138 °C(lit.)

[ Molecular Formula ]:
C₂H₇N₃S

[ Molecular Weight ]:
105.162

[ Flash Point ]:
55.6±22.6 °C

[ Exact Mass ]:
105.036064

[ PSA ]:
82.17000

[ LogP ]:
-0.82

[ Vapour Pressure ]:
1.6±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.582

[ Storage condition ]:
Poison room

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MV1407370

CHEMICAL NAME :: Hydrazinecarbothioamide, N-methyl-

CAS REGISTRY NUMBER :: 6610-29-3

LAST UPDATED :: 199710

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C2-H7-N3-S

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 14 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Gastrointestinal - changes in structure or function of salivary glands Gastrointestinal - hypermotility, diarrhea

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571100

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300

[ Precautionary Statements ]:
P264-P301 + P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
T+:Verytoxic;

[ Risk Phrases ]:
R28

[ Safety Phrases ]:
S45-S28A-S1

[ RIDADR ]:
UN 2811 6.1/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
MV1407370

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1

[ HS Code ]:
2930909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Electronic features and hydrogen bonding capacity of the sulfur acceptor in thioureido-based compounds. Experimental charge density study of 4-methyl-3-thiosemicarbazide. Francuski BM, et al., DOI: 10.1039/C0CE00760A

CrystEngComm 13 , 3580-3591, (2011)