(1R)-(-)-(1-AMINOPROPYL)PHOSPHONICACID
Names
[ CAS No. ]:
66254-56-6
[ Name ]:
(1R)-(-)-(1-AMINOPROPYL)PHOSPHONICACID
[Synonym ]:
MFCD00797884
[(1R)-1-amino-2-methylpropyl]phosphonic acid
Chemical & Physical Properties
[ Density]:
1.295g/cm3
[ Boiling Point ]:
302.9ºC at 760 mmHg
[ Melting Point ]:
272-277ºC(lit.)
[ Molecular Formula ]:
C4H12NO3P
[ Molecular Weight ]:
153.11700
[ Flash Point ]:
137ºC
[ Exact Mass ]:
153.05500
[ PSA ]:
93.36000
[ LogP ]:
0.80520
[ Index of Refraction ]:
1.486
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2931900090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2931900090
[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%
Articles
Science 265 , 234, (1994)
Monoclonal antibodies, induced with a phosphonate diester hapten, catalyzed the coupling of p-nitrophenyl esters of N-acetyl valine, leucine, and phenylalanine with tryptophan amide to form the corres...
Synthesis and structure-activity relationships of antibacterial phosphonopeptides incorporating (1-aminoethyl)phosphonic acid and (aminomethyl)phosphonic acid.J. Med. Chem. 29 , 29, (1986)
Phosphonodipeptides and phosphonooligopeptides based on L- and D-(1-aminoethyl)phosphonic acids L-Ala(P) and D-Ala(P) and (aminomethyl)phosphonic acid Gly(P) at the acid terminus have been synthesized...
New alpha-amino phosphonic acid derivatives of vinblastine: chemistry and antitumor activity.J. Med. Chem. 34 , 1998, (1991)
A series of new amino phosphonic acid derivatives of vinblastine (1, VLB) has been synthesized and tested in vitro and in vivo for antitumor activity. The compounds were obtained from O4-deacetyl-VLB ...