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(1R)-(-)-(1-AMINOPROPYL)PHOSPHONICACID

Names

[ CAS No. ]:
66254-56-6

[ Name ]:
(1R)-(-)-(1-AMINOPROPYL)PHOSPHONICACID

[Synonym ]:
MFCD00797884
[(1R)-1-amino-2-methylpropyl]phosphonic acid

Chemical & Physical Properties

[ Density]:
1.295g/cm3

[ Boiling Point ]:
302.9ºC at 760 mmHg

[ Melting Point ]:
272-277ºC(lit.)

[ Molecular Formula ]:
C4H12NO3P

[ Molecular Weight ]:
153.11700

[ Flash Point ]:
137ºC

[ Exact Mass ]:
153.05500

[ PSA ]:
93.36000

[ LogP ]:
0.80520

[ Index of Refraction ]:
1.486

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2931900090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2931900090

[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

Articles

Peptide synthesis catalyzed by an antibody containing a binding site for variable amino acids.

Science 265 , 234, (1994)

Monoclonal antibodies, induced with a phosphonate diester hapten, catalyzed the coupling of p-nitrophenyl esters of N-acetyl valine, leucine, and phenylalanine with tryptophan amide to form the corres...

Synthesis and structure-activity relationships of antibacterial phosphonopeptides incorporating (1-aminoethyl)phosphonic acid and (aminomethyl)phosphonic acid.

J. Med. Chem. 29 , 29, (1986)

Phosphonodipeptides and phosphonooligopeptides based on L- and D-(1-aminoethyl)phosphonic acids L-Ala(P) and D-Ala(P) and (aminomethyl)phosphonic acid Gly(P) at the acid terminus have been synthesized...

New alpha-amino phosphonic acid derivatives of vinblastine: chemistry and antitumor activity.

J. Med. Chem. 34 , 1998, (1991)

A series of new amino phosphonic acid derivatives of vinblastine (1, VLB) has been synthesized and tested in vitro and in vivo for antitumor activity. The compounds were obtained from O4-deacetyl-VLB ...


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Related Compounds