N-[6-[[(1S,3S)-3-(1,2-dihydroxyethyl)-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-3-hydroxy-2-methyl-oxan-4-yl]-2,2,2-trifluoro-acetamide
Names
[ CAS No. ]:
66512-17-2
[ Name ]:
N-[6-[[(1S,3S)-3-(1,2-dihydroxyethyl)-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-3-hydroxy-2-methyl-oxan-4-yl]-2,2,2-trifluoro-acetamide
[Synonym ]:
N-trifluoroacetyladriamycinol
AD-92
Chemical & Physical Properties
[ Density]:
1.66g/cm3
[ Boiling Point ]:
872.9ºC at 760 mmHg
[ Molecular Formula ]:
C29H30F3NO12
[ Molecular Weight ]:
641.54300
[ Flash Point ]:
481.7ºC
[ Exact Mass ]:
641.17200
[ PSA ]:
212.31000
[ LogP ]:
0.90380
[ Index of Refraction ]:
1.662
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QI9420000
- CHEMICAL NAME :
- 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-8-(1,2-dihydroxyethyl)-1-methoxy- 10-((2,3,6- trideoxy-2-(trifluoroacetamido)-alpha-L-lyxo-hexopyra nosyl)oxy)-6,8,11-tri hydroxy-
- CAS REGISTRY NUMBER :
- 66512-17-2
- LAST UPDATED :
- 198207
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C29-H30-F3-N-O12
- MOLECULAR WEIGHT :
- 641.60
- WISWESSER LINE NOTATION :
- L E6 C666 BV MVT&&&J DQ HYQ1Q HQ KQ RO1 FO- FT6OTJ B1 CQ DMVXFFF
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Rodent - mouse Leukocyte
- DOSE/DURATION :
- 43700 nmol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 41,1006,1981