Barbituric acid
Names
[ CAS No. ]:
67-52-7
[ Name ]:
Barbituric acid
[Synonym ]:
Pyrimidinetriol
Hydrouracil, 6-hydroxy-
Barbitursure
Balonylurea acid
T6VMVMV FHJ
Barbituric acid
N,N'-MALONYLUREA
barbituric
2,4,6-Trioxohexahydropyrimidine
Malonylurea
Pyrimidin-2,4,6(1H,3H,5H)-trion
2,4,6-Pyrimidinetrione
pyrimidine-2,4,6-trione
2,4,6(1H,3H,5H)-Pyrimidinetrione
ARBIBTONE ACID
4,6-Dihydroxy-2(5H)-pyrimidinone
2,4,6-Trihydroxypyrimidine
6-HYDROXYURACIL
EINECS 200-658-0
2(5H)-Pyrimidinone, 4,6-dihydroxy-
pyrimidine-2,4,6(1H,3H,5H)-trione
MFCD00006666
BarbituricAcidGr
Chemical & Physical Properties
[ Density]:
1.8±0.1 g/cm3
[ Boiling Point ]:
372.7±25.0 °C at 760 mmHg
[ Melting Point ]:
248-252 °C (dec.)(lit.)
[ Molecular Formula ]:
C4H4N2O3
[ Molecular Weight ]:
128.086
[ Flash Point ]:
179.2±23.2 °C
[ Exact Mass ]:
128.022186
[ PSA ]:
75.27000
[ LogP ]:
-1.72
[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C
[ Index of Refraction ]:
1.709
[ Water Solubility ]:
142 g/L (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CP8000000
- CHEMICAL NAME :
- Barbituric acid
- CAS REGISTRY NUMBER :
- 67-52-7
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C4-H4-N2-O3
- MOLECULAR WEIGHT :
- 128.10
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 18,185,1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 505 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 106,504,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81718 No. of Facilities: 28 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 700 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81718 No. of Facilities: 79 (estimated) No. of Industries: 4 No. of Occupations: 5 No. of Employees: 3529 (estimated) No. of Female Employees: 1481 (estimated)
Safety Information
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S24/25
[ WGK Germany ]:
1
[ RTECS ]:
CP8000000
[ HS Code ]:
2933520000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933520000
[ Summary ]:
HS: 2933520000. pyrimidine-2,4,6(1h,3h,5h)-trione. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tarrif:6.5%. general tariff:20.0%