Triamcinolone diacetate

Names

[ CAS No. ]:
67-78-7

[ Name ]:
Triamcinolone diacetate

[Synonym ]:
Kenacourt
CINO-40
Triamolone 40
Pregna-1,4-diene-3,20-dione, 16,21-bis(acetyloxy)-9-fluoro-11,17-dihydroxy-, (11β,16α)-
(11β,16α)-9-Fluoro-11,17-dihydroxy-3,20-dioxopregna-1,4-diene-16,21-diyl diacetate
21-diacetate
16a,21-Diacetoxy-9a-fluoro-11b,17a-dihydroxy-1,4-pregnadiene-3,20-dione
aristocortsyrup
8357RP
Tracilon
Tedarol
TAC-D
triamcinolone 16,21-diacetate
MFCD00056462
EINECS 200-669-0
(11b,16a)-16,21-Bis(acetyloxy)-9-fluoro-11,17-dihydroxypregna-1,4-diene-3,20-dione
Cenacort
Triamsinolone

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
608.5±55.0 °C at 760 mmHg

[ Melting Point ]:
19-21°C

[ Molecular Formula ]:
C₂₅H₃₁FO₈

[ Molecular Weight ]:
478.507

[ Flash Point ]:
321.8±31.5 °C

[ Exact Mass ]:
478.200287

[ PSA ]:
127.20000

[ LogP ]:
2.16

[ Vapour Pressure ]:
0.0±4.0 mmHg at 25°C

[ Index of Refraction ]:
1.573

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TU3950000

CHEMICAL NAME :: Pregna-1,4-diene-2,20-dione, 9-fluoro-11-beta,16-alpha,17,21-tetrahydroxy-, 16,21-diacetate

CAS REGISTRY NUMBER :: 67-78-7

LAST UPDATED :: 199710

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C25-H31-F-O8

MOLECULAR WEIGHT :: 478.56

WISWESSER LINE NOTATION :: T F5 E5 B666 GO IO RV AHTTTT&J A1 BF COV1 E1 FV1OV1 H1 H1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 87500 ug/kg

SEX/DURATION :: female 15-17 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - extra-embryonic structures (e.g., placenta, umbilical cord)

REFERENCE :: BBACAQ Biochimica et Biophysica Acta. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1947- Volume(issue)/page/year: 385,257,1975

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 3200 ug/kg

SEX/DURATION :: female 11-14 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)

REFERENCE :: SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 149,862,1965 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81555 No. of Facilities: 44 (estimated) No. of Industries: 1 No. of Occupations: 4 No. of Employees: 1469 (estimated) No. of Female Employees: 1098 (estimated)

Safety Information

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R10:Flammable.

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 3272 3/PG 3

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
29349990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 29349990