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Methotrexate gamma-Methyl Ester

Names

[ CAS No. ]:
67022-39-3

[ Name ]:
Methotrexate gamma-Methyl Ester

[Synonym ]:
(2S)-2-((4-(((2,4-Diaminopteridin-6-yl)methyl)methylamino)benzoyl)amino)-5-methoxy-5-oxopentanoic acid
L-Glutamic acid,N-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-,5-methyl ester
Methotrexate related compound H [USP]
Methotrexate related compound H
Methotrexate specified impurity H [EP]
Methotrexate 5-methyl ester
Methotrexate gamma-Methyl Ester
Methotrexate γ-Methyl Ester

Biological Activity

[Description]:

Methotrexate γ-Methyl Ester (Methotrexate 5-methyl ester) is an impurity of the folate antagonist Methotrexate (HY-14519)[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. James J Fort, et al. Transport and degradation characteristics of methotrexate diallsyl ester prodrugs across tape-stripped hairless mouse skin. Int J Pharm. 1993, 100(1-3): 233-239.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H24N8O5

[ Molecular Weight ]:
468.47

[ Exact Mass ]:
468.18700

[ PSA ]:
200.27000

[ LogP ]:
1.25900

Related Compounds