BETA-CHLORNALTREXAMINE 2HCL

[ Molecular Formula ]:
C₂₄H₃₄Cl₄N₂O₃

[ Molecular Weight ]:
540.35000

[ Exact Mass ]:
538.13200

[ PSA ]:
56.17000

[ LogP ]:
4.64640

Click to get detail MSDS

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
QC7792000

Methocinnamox is a potent, long-lasting, and selective antagonist of morphine-mediated antinociception in the mouse: comparison with clocinnamox, beta-funaltrexamine, and beta-chlornaltrexamine.

J. Pharmacol. Exp. Ther. 294 , 933, (2000)

The irreversible mu-opioid antagonists beta-funaltrexamine (beta-FNA) and beta-chlornaltrexamine (beta-CNA) are important pharmacological tools but have a kappa-agonist activity and, in the latter cas...

Relationship between kappa 1 opioid receptor binding and inhibition of adenylyl cyclase in guinea pig brain membranes.

Biochem. Pharmacol. 45(1) , 207-16, (1993)

Previously, we showed that kappa-selective ligands inhibit adenylyl cyclase in guinea pig cerebellar membranes. The present studies explore the relationship between kappa 1 binding sites (as determine...

Single nucleotide polymorphisms in the human mu opioid receptor gene alter basal G protein coupling and calmodulin binding.

J. Biol. Chem. 276(37) , 34624-30, (2001)

The mu opioid receptor (MOR) plays a central role in mediating acute and chronic effects of narcotic drugs. Three rare single nucleotide polymorphisms in the hMOR gene have been identified that cause ...

More Articles