1-Nitrosoguanidine
Names
[ CAS No. ]:
674-81-7
[ Name ]:
1-Nitrosoguanidine
[Synonym ]:
1-Nitrosoguanidine
Nitrosoguanidine
Nitrosoguanidines
Nitrosoguanidin
MFCD00059593
N-Nitrosoguanidine
GUANIDINE,NITROSO
Guanidine, N-nitroso-
Chemical & Physical Properties
[ Density]:
1.8±0.1 g/cm3
[ Boiling Point ]:
131.6±23.0 °C at 760 mmHg
[ Molecular Formula ]:
CH4N4O
[ Molecular Weight ]:
88.069
[ Flash Point ]:
33.4±22.6 °C
[ Exact Mass ]:
88.038513
[ PSA ]:
91.33000
[ LogP ]:
-1.25
[ Vapour Pressure ]:
9.2±0.2 mmHg at 25°C
[ Index of Refraction ]:
1.665
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MF4725000
- CHEMICAL NAME :
- Guanidine, nitroso-
- CAS REGISTRY NUMBER :
- 674-81-7
- LAST UPDATED :
- 199406
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C-H4-N4-O
- MOLECULAR WEIGHT :
- 88.09
- WISWESSER LINE NOTATION :
- ONMYZUM
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Behavioral - ataxia Gastrointestinal - hypermotility, diarrhea Kidney, Ureter, Bladder - other changes in urine composition
- REFERENCE :
- ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 12,563,1993
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 12,563,1993
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 21 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 23,288,1972
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 12,563,1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83966 No. of Facilities: 61 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 442 (estimated)
Safety Information
[ Risk Phrases ]:
11-20/21/22-36/37/38
[ Safety Phrases ]:
S16;S26;S36/S37/S39
[ RIDADR ]:
UN 1325