2-Chloro-N-methoxy-N-methylacetamide
Names
[ CAS No. ]:
67442-07-3
[ Name ]:
2-Chloro-N-methoxy-N-methylacetamide
[Synonym ]:
2-Chloro-N-methoxy-N-methylacetamide
Acetamide, 2-chloro-N-methoxy-N-methyl-
MFCD00134232
G1VN1&O1
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
141.5±42.0 °C at 760 mmHg
[ Melting Point ]:
39-41 °C(lit.)
[ Molecular Formula ]:
C4H8ClNO2
[ Molecular Weight ]:
137.565
[ Flash Point ]:
104.4±0.0 °C
[ Exact Mass ]:
137.024353
[ PSA ]:
29.54000
[ LogP ]:
-0.08
[ Vapour Pressure ]:
5.8±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.443
[ Storage condition ]:
Refrigerator
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H312-H332
[ Precautionary Statements ]:
P280
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S23-S26-S27-S28-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2924199090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2924199090
[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Org. Biomol. Chem. 9(1) , 57-61, (2011)
Expedient syntheses of Pseudomonas quinolone signal (PQS) and related structural analogues using microwave and flow methods are reported.
Microwave-assisted preparation of the quorum-sensing molecule 2-heptyl-3-hydroxy-4(1H)-quinolone and structurally related analogs.Nat. Protoc. 7(6) , 1184-92, (2012)
An optimized procedure for the efficient preparation of 2-heptyl-3-hydroxy-4(1H)-quinolone (Pseudomonas quinolone signal or PQS) and a diverse range of structurally related 2-alkyl-4-quinolones with b...
New Reagent for Convenient Access to the a, ß-Unsaturated N-Methoxy-N-methyl-amide Functionality by a Synthesis Based on the Julia Olefination Protocol. Narayana Manjunath B, et alEuropean J. Org. Chem. 12 , 2851-55, (2006)