6-Fluorosalicylic Acid

Names

[ Name ]:
6-Fluorosalicylic Acid

[Synonym ]:
2-Fluoro-6-hydroxybenzoic acid
QVR BQ FF
2-Fluoro-6-hydroxybenzoicacid
6-Fluorosalicylic Acid
Benzoic acid, 2-fluoro-6-hydroxy-
6-Fluoro-2-hydroxybenzoic acid
MFCD00052179
2-Fluoro-6-hydroxylbenzoic acid

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
291.2±25.0 °C at 760 mmHg

[ Melting Point ]:
159-163 °C(lit.)

[ Molecular Formula ]:
C₇H₅FO₃

[ Molecular Weight ]:
156.111

[ Flash Point ]:
129.9±23.2 °C

[ Exact Mass ]:
156.022278

[ PSA ]:
57.53000

[ LogP ]:
2.42

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.585

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H318

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R41

[ Safety Phrases ]:
S26-S39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2918290000

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2918290000

[ Summary ]:
HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

Articles

Harnessing Enzymatic Promiscuity in Myxochelin Biosynthesis for the Production of 5-Lipoxygenase Inhibitors.

ChemBioChem. 16(17) , 2445-50, (2015)

The siderophore myxochelin A is a potent inhibitor of human 5-lipoxygenase (5-LO). To clarify whether the iron-chelating properties of myxochelin A are responsible for this activity, several analogues...

Inhibitors of hepatitis C virus polymerase: synthesis and characterization of novel 2-oxy-6-fluoro-N-((S)-1-hydroxy-3-phenylpropan-2-yl)-benzamides. Cheng CC, et al.

Bioorg. Med. Chem. Lett. 20(7) , 2119-24, (2010)