1,3-diacetylbenzene

Names

[ Name ]:
1,3-diacetylbenzene

[Synonym ]:
EINECS 229-842-9
1,3-diacetylbenzene
1-(3-acetylphenyl)ethanone
Ethanone, 1,1'-(1,3-phenylene)bis-
1,1'-benzene-1,3-diyldiethanone
MFCD00008740
1,1'-(1,3-Phenylene)diethanone

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
280.3±0.0 °C at 760 mmHg

[ Melting Point ]:
28-32 °C(lit.)

[ Molecular Formula ]:
C₁₀H₁₀O₂

[ Molecular Weight ]:
162.185

[ Flash Point ]:
108.5±19.6 °C

[ Exact Mass ]:
162.068085

[ PSA ]:
34.14000

[ LogP ]:
1.43

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.519

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2914399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914399090

[ Summary ]:
2914399090. other aromatic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

Amino acid and protein targets of 1,2-diacetylbenzene, a potent aromatic gamma-diketone that induces proximal neurofilamentous axonopathy.

Toxicol. Appl. Pharmacol. 183(1) , 55-65, (2002)

The gamma-diketone analogs 1,2-diacetylbenzene (1,2-DAB) and 2,5-hexanedione (2,5-HD), but not the delta-diketone 1,3-diacetylbenzene (1,3-DAB) or the beta-diketone 2,4-hexanedione, induce neuropathol...

Geometrically and conformationally restrained cinnamoyl compounds as inhibitors of HIV-1 integrase: synthesis, biological evaluation, and molecular modeling.

J. Med. Chem. 41(21) , 3948-60, (1998)

Various cinnammoyl-based structures were synthesized and tested in enzyme assays as inhibitors of the HIV-1 integrase (IN). The majority of compounds were designed as geometrically or conformationally...