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Formamide,N,N'-(sulfonyldi-4,1-phenylene)bis- (9CI)

Names

[ CAS No. ]:
6784-25-4

[ Name ]:
Formamide,N,N'-(sulfonyldi-4,1-phenylene)bis- (9CI)

[Synonym ]:
Diformyl-4,4'-sulfonyldianiline
4',4''-sulfonyldiformanilide
Diformyldapsone
p,p'-Sulfonylbisformanilide
WR 6798
Formilone
DFDDS
Diformyl diaminodiphenylsulfone
4,4'-Diformamidodiphenyl sulfone

Chemical & Physical Properties

[ Density]:
1.439g/cm3

[ Boiling Point ]:
643.4ºC at 760 mmHg

[ Molecular Formula ]:
C14H12N2O4S

[ Molecular Weight ]:
304.32100

[ Flash Point ]:
342.9ºC

[ Exact Mass ]:
304.05200

[ PSA ]:
100.72000

[ LogP ]:
4.15460

[ Index of Refraction ]:
1.654

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WR4550000
CHEMICAL NAME :
Sulfone, bis(N-formyl-p-aminophenyl)
CAS REGISTRY NUMBER :
6784-25-4
BEILSTEIN REFERENCE NO. :
2815334
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C14-H12-N2-O4-S
MOLECULAR WEIGHT :
304.34
WISWESSER LINE NOTATION :
VHMR DSWR DMVH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
450 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 18,469,1971
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
760 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EXPAAA Experimental Parasitology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 20,88,1967
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
98 mg/kg
TOXIC EFFECTS :
Vascular - BP lowering not characterized in autonomic section Cardiac - change in rate
REFERENCE :
IJLEAG International Journal of Leprosy and Other Mycobacterial Diseases. (POB 1097, Bloomfield, NJ 07003) V.1- 1933- Volume(issue)/page/year: 36,432,1968
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
255 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Vascular - BP lowering not characterized in autonomic section
REFERENCE :
IJLEAG International Journal of Leprosy and Other Mycobacterial Diseases. (POB 1097, Bloomfield, NJ 07003) V.1- 1933- Volume(issue)/page/year: 36,432,1968

Safety Information

[ HS Code ]:
2924299090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%