(S)-(+)-Epichlorhydrin

Names

[ Name ]:
(S)-(+)-Epichlorhydrin

[Synonym ]:
MFCD00005132
EINECS 203-439-8
Oxirane, 2-(chloromethyl)-, (2S)-
T3OTJ B1G &&(S)-(+)- Form
(S)-3-Chloropropylene Oxide
(S)-(+)-Epichlorohydrin
(2S)-2-(Chloromethyl)oxirane
5-17-01-00021 (Beilstein Handbook Reference)
(S)-(+)-2-(CHLOROMETHYL) OXIRANE

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
116.1±0.0 °C at 760 mmHg

[ Melting Point ]:
−57 °C(lit.)

[ Molecular Formula ]:
C₃H₅ClO

[ Molecular Weight ]:
92.524

[ Flash Point ]:
33.9±0.0 °C

[ Exact Mass ]:
92.002892

[ PSA ]:
12.53000

[ LogP ]:
0.45

[ Vapour density ]:
3.2 (vs air)

[ Vapour Pressure ]:
22.0±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.444

[ Water Solubility ]:
insoluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RR0427100

CHEMICAL NAME :: Oxirane, (chloromethyl)-, (S)-

CAS REGISTRY NUMBER :: 67843-74-7

BEILSTEIN REFERENCE NO. :: 1420784

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C3-H5-Cl-O

MOLECULAR WEIGHT :: 92.53

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 298,197,1993

Safety Information

[ Symbol ]:

GHS02, GHS05, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H226-H301 + H311 + H331-H314-H317-H350

[ Precautionary Statements ]:
P201-P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338-P308 + P313

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
T:Toxic

[ Risk Phrases ]:
R10;R23/24/25;R34;R43;R45

[ Safety Phrases ]:
S53-S45

[ RIDADR ]:
UN 2023 6.1/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
TX4900000

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1

[ HS Code ]:
2910900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2910900090

[ Summary ]:
2910900090. epoxides, epoxyalcohols, epoxyphenols and epoxyethers, with a three-membered ring, and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

Kinetics of dextran crosslinking by epichlorohydrin: a rheometry and equilibrium swelling study.

Carbohydr. Polym. 92(2) , 1792-8, (2013)

Curing behavior and gel properties of dextran are investigated during its crosslinking by epichlorohydrin (ECH) using rheometry and equilibrium swelling studies. Each ECH/anhydroglucose unit of differ...

Adsorptive decolorization of methylene blue by crosslinked porous starch.

Carbohydr. Polym. 93(2) , 374-9, (2013)

Crosslinked porous starch (CPS) was prepared by two steps. Native starch was crosslinked with epichlorohydrin and then CPS was prepared by hydrolyzing the crosslinked starch with α-amylase. As a biode...

Genotoxic effects of ethylene oxide, propylene oxide and epichlorohydrin in humans: update review (1990-2001).

Mutat. Res. 512(2-3) , 173-94, (2002)

Ethylene oxide (EtO), propylene oxide (PO) and epichlorohydrin (ECH) are important industrial chemicals widely used as intermediates for various synthetic products. EtO and PO are also environmental p...