4-Bromophenoxy t-Butyl-Dimethylsilane

Names

[ Name ]:
4-Bromophenoxy t-Butyl-Dimethylsilane

[Synonym ]:
(4-bromophenoxy)-tert-butyl-dimethylsilane
MFCD00239382
4-Bromophenol tert-Butyldimethylsilyl Ether
Benzene, 1-bromo-4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-
(4-Bromophenoxy)-tert-butyldimethylsilane
(4-Bromophenoxy)(dimethyl)(2-methyl-2-propanyl)silane
(4-Bromphenoxy)(tert-butyl)dimethylsilan
(4-Bromophenoxy)(tert-butyl)dimethylsilane
4-Bromophenoxy t-Butyl-Dimethylsilane

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
264.0±23.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₂H₁₉BrOSi

[ Molecular Weight ]:
287.268

[ Flash Point ]:
113.5±22.6 °C

[ Exact Mass ]:
286.038849

[ PSA ]:
9.23000

[ LogP ]:
1.62

[ Appearance of Characters ]:
Liquid | Colorless

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.496

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H315-H319-H335

[ Precautionary Statements ]:
P210-P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F,Xi

[ Risk Phrases ]:
R11

[ Safety Phrases ]:
16-26-36

[ RIDADR ]:
UN 1993 3/PG 2

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Articles

Synthesis and PTP1B inhibition of 1,2-naphthoquinone derivatives as potent anti-diabetic agents.

Bioorg. Med. Chem. Lett. 12(15) , 1941-6, (2002)

A new series of 1,2-naphthoquinone derivatives was synthesized by various synthetic methods and evaluated for their ability to inhibit protein tyrosine phosphatase 1B (PTP1B). 1,2-Naphthoquinone deriv...