Diethyl isopropylidenemalonate

Names

[ Name ]:
Diethyl isopropylidenemalonate

[Synonym ]:
Diethyl isopropylidenemalonate
diethyl 2-propan-2-ylidenepropanedioate
EINECS 229-876-4
Propanedioic acid, (1-methylethylidene)-, diethyl ester
Malonic acid, isopropylidene-, diethyl ester
Propanedioic acid, 2-(1-methylethylidene)-, diethyl ester
MFCD00009147

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
242.8±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₀H₁₆O₄

[ Molecular Weight ]:
200.232

[ Flash Point ]:
109.4±0.0 °C

[ Exact Mass ]:
200.104858

[ PSA ]:
52.60000

[ LogP ]:
2.79

[ Vapour Pressure ]:
0.0±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.446

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S23-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2917190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2917190090

[ Summary ]:
2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Terminal bifunctional retinoids. Synthesis and evaluations related to cancer chemopreventive activity.

J. Med. Chem. 31(6) , 1124-30, (1988)

Retinoids that have two functional groups at the side-chain terminus have been synthesized. The two terminal functional groups are combinations of the carboxyl, carbethoxy, and N-(ethylamino)carbonyl ...

Reduction of alkylidenecyanoacetates with sodium borohydride. Marshall JA and Carroll RD.

J. Org. Chem. 30(8) , 2748-54, (1965)