2-amino-4-methylsulfanylbutanoic acid

Names

[ CAS No. ]:
68799-90-6

[ Name ]:
2-amino-4-methylsulfanylbutanoic acid

[Synonym ]:
13C-methionine
DL-Methionine-1-13C
I09-3017
MFCD00084011

Biological Activity

[Description]:

DL-Methionine-13C is the 13C-labeled DL-Methionine. DL-Methionine is an essential amino acid containing sulfur with oxidative stress defense effects. DL-Methionine can be used for animal natural feed. DL-Methionine also kills H. rostochiensis on potato plants[1][2][3].

[Related Catalog]:

Research Areas >> Infection
Research Areas >> Inflammation/Immunology

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. K. evans, et al. Effects of amino acids on the reproduction of Heterodera rostochiensis. Nematologica, 1971, 17(4), 495-500.

[3]. Swennen Q, et al. Effects of dietary protein content and 2-hydroxy-4-methylthiobutanoic acid or DL-methionine supplementation on performance and oxidative status of broiler chickens. Br J Nutr. 2011 Dec;106(12):1845-54.

[4]. Garlich JD. Response of broilers to DL-methionine hydroxy analog free acid, DL-methionine, and L-methionine. Poult Sci. 1985 Aug;64(8):1541-8.

Chemical & Physical Properties

[ Density]:
1.206g/cm3

[ Melting Point ]:
280ºC (dec.)(lit.)

[ Molecular Formula ]:
C5H11NO2S

[ Molecular Weight ]:
150.20400

[ Exact Mass ]:
150.05400

[ PSA ]:
88.62000

[ LogP ]:
0.85170

[ Index of Refraction ]:
1.53

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route


Related Compounds