Germacrone

Names

[ Name ]:
Germacrone

[Synonym ]:
(3E,7E)-10-Isopropylidene-3,7-dimethyl-3,7-cyclodecadien-1-one
3,7-Cyclodecadien-1-one, 3,7-dimethyl-10-(1-methylethylidene)-, (E,E)-
(7E)-3,7-dimethyl-10-(propan-2-ylidene)cyclodeca-3,7-dien-1-one
3,7-Cyclodecadien-1-one, 3,7-dimethyl-10-(1-methylethylidene)-, (3E,7E)-
(3E,7E)-3,7-dimethyl-10-propan-2-ylidenecyclodeca-3,7-dien-1-one
(3E,7E)-10-Isopropylidene-3,7-dimethylcyclodeca-3,7-dien-1-one
3,7-Cyclodecadien-1-one, 3,7-dimethyl-10-(1-methylethylidene)-, (3Z,7Z)-
(3E,7E)-3,7-dimethyl-10-(propan-2-ylidene)cyclodeca-3,7-dien-1-one
(3Z,7Z)-10-Isopropylidene-3,7-dimethyl-3,7-cyclodecadien-1-one
Germacrone

Biological Activity

[Description]:

Germacrone is extracted from Rhizoma Curcuma. Germacrone inhibits influenza virus infection[1].

[Related Catalog]:

Research Areas >> Infection

[Target]

Influenza virus[1]

[References]

[1]. Liao Q, et al. Germacrone inhibits early stages of influenza virus infection. Antiviral Res. 2013 Dec;100(3):578-88.

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
330.3±42.0 °C at 760 mmHg

[ Melting Point ]:
55-58ºC

[ Molecular Formula ]:
C₁₅H₂₂O

[ Molecular Weight ]:
218.335

[ Flash Point ]:
148.4±18.7 °C

[ Exact Mass ]:
218.167068

[ PSA ]:
17.07000

[ LogP ]:
4.76

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.485

[ Storage condition ]:
2-8°C

Safety Information

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
23-24/25

[ RTECS ]:
GU2210000

[ HS Code ]:
2914299000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914299000

[ Summary ]:
2914299000. other cyclanic, cyclenic or cyclotherpenic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%