N6-acetyl-L-lysine

Names

[ CAS No. ]:
692-04-6

[ Name ]:
N6-acetyl-L-lysine

[Synonym ]:
Ne-Acetyl-L-lysine
Ne-Acetyllysine
MFCD00002639
N-ε-ACETYL-L-LYSINE
L-Lysine, N-acetyl-
N(6)-acetyl-L-lysine
(S)-6-Acetamido-2-aminohexanoic acid
L-Lysine, N-(1-hydroxyethylidene)-, (Z)-
N-Acetyl-L-lysine
(Z)-N-(1-Hydroxyethylidene)-L-lysine
EINECS 211-725-9
H-Lys(Ac)-OH
N-epsilon-Acetyl-L-lysine
Nε-Acetyl-L-lysine

Biological Activity

[Description]:

Nepsilon-Acetyl-L-lysine is a derivative of the amino acid lysine.

[Related Catalog]:

Natural Products >> Others

Research Areas >> Others

[Target]

Human Endogenous Metabolite

[References]

[1]. Schmidt H, et al. Characterization of a novel enzyme, N6-acetyl-L-lysine: 2-oxoglutarate aminotransferase, which catalyses the second step of lysine catabolism in Candida maltosa. Antonie Van Leeuwenhoek. 1992 Nov;62(4):285-90.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
442.0±40.0 °C at 760 mmHg

[ Melting Point ]:
250 °C (dec.)(lit.)

[ Molecular Formula ]:
C₈H₁₆N₂O₃

[ Molecular Weight ]:
188.224

[ Flash Point ]:
221.1±27.3 °C

[ Exact Mass ]:
188.116089

[ PSA ]:
92.42000

[ LogP ]:
-1.42

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.490

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29241900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Hypernuclear acetylation in atherosclerotic lesions and activated vascular smooth muscle cells.

Biochem. Biophys. Res. Commun. 266(2) , 417-24, (1999)

Recent studies have implicated acetylation of several nuclear proteins such as histones and p53 on their epsilon-portion of lysine residues in eukaryotic transcription. Here we raised a specific polyc...

Proteomic analysis of organ-specific post-translational lysine-acetylation and -methylation in mice by use of anti-acetyllysine and -methyllysine mouse monoclonal antibodies.

Proteomics 5(18) , 4653-64, (2005)

Post-translational lysine-acetylation and -methylation are two major PTMs of lysine residues in proteins. Recently, we established pan-reactive anti-acetyllysine mouse mAbs, which can bind to Nepsilon...

Purification and characterization of a novel aminoacylase from Streptomyces mobaraensis.

Biosci. Biotechnol. Biochem. 69 , 1914-1922, (2005)

A novel aminoacylase was purified to homogeneity from culture broth of Streptomyces mobaraensis, as evidenced by SDS-polyacrylamide gel electrophoresis (PAGE). The enzyme was a monomer with an approxi...