Buprofezin

Names

[ Name ]:
Buprofezin

[Synonym ]:
Buprofezin
VIAPPLA
PP618
Aproad
APPLAUD
Buprofenzin
Appland
BUTYL
MFCD01681899
BUPROLEX
NNI 750

Biological Activity

[Description]:

Buprofezin is an insecticide that acts by inhibiting chitin synthesis. Buprofezin also dose-dependently increases the production of reactive oxygen species (ROS) in vitro.

Chemical & Physical Properties

[ Density]:
1.18

[ Boiling Point ]:
273°C (12 torr)

[ Melting Point ]:
104-106°C

[ Molecular Formula ]:
C₁₆H₂₃N₃OS

[ Molecular Weight ]:
305.43800

[ Flash Point ]:
176-178°C

[ Exact Mass ]:
305.15600

[ PSA ]:
61.21000

[ LogP ]:
4.18510

[ Index of Refraction ]:
1.52-1.522

[ Water Solubility ]:
0.9 mg/L at 20 ºC

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XI2865000

CHEMICAL NAME :: 4H-1,3,5-Thiadiazin-4-one, 2-((1,1-dimethylethyl)imino)tetrahydro-3-(1-methyleth yl)-5-phenyl-

CAS REGISTRY NUMBER :: 69327-76-0

LAST UPDATED :: 199612

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C16-H23-N3-O-S

MOLECULAR WEIGHT :: 305.48

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2198 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Morphological transformation

TEST SYSTEM :: Rodent - hamster Embryo

DOSE/DURATION :: 12500 nmol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 303,121,1993

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
XI2865000

Articles

Effect of repeated applications of buprofezin and acephate on soil cellulases, amylase, and invertase.

Environ. Monit. Assess. 186(10) , 6319-25, (2014)

The impact of repeated applications of buprofezin and acephate, at concentrations ranging from 0.25 to 1.0 kg ha(-1), on activities of cellulases, amylase, and invertase in unamended and nitrogen, pho...

Effects of pyriproxyfen and buprofezin on immature development and reproduction in the stable fly.

Med. Vet. Entomol. 26(4) , 379-85, (2012)

The stable fly, Stomoxys calcitrans (L.) (Diptera: Muscidae), is one of the most significant biting flies that affect cattle. The use of traditional insecticides for stable fly control has only a limi...

Action threshold for applying insect growth regulators to tomato for management of irregular ripening caused by Bemisia argentifolii (Homoptera: Aleyrodidae).

J. Econ. Entomol. 95(2) , 372-6, (2002)

The whitefly Bemisia argentifolii Bellows & Perring is a major pest of tomatoes, causing an irregular ripening disorder characterized externally by incomplete or inhibited reddening of fruit, especial...