4-HYDROXY-6-OXO-1,6-DIHYDRO-1,3,5-TRIAZINE-2-CARBOXAMIDE

Names

[ Name ]:
4-HYDROXY-6-OXO-1,6-DIHYDRO-1,3,5-TRIAZINE-2-CARBOXAMIDE

[Synonym ]:
Oxonsaeureamid
4,6-dioxo-1,4,5,6-tetrahydro-1,3,5-triazine-2-carboxamide
Allantoxanamide
Oxonamide

Biological Activity

[Description]:

Allantoxanamide is a uricase inhibitor. Allantoxanamide-induced rats serve as animal models for studying purine biosynthesis, drug-induced hyperuricemia and hyperuricosuria, and related nephropathy[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[Target]

Uricase[1].

[References]

[1]. Johnson WJ, Chartrand A. Allantoxanamide: a potent new uricase inhibitor in vivo. Life Sci. 1978 Nov 27;23(22):2239-44.

Chemical & Physical Properties

[ Density]:
2.19g/cm3

[ Molecular Formula ]:
C₄H₄N₄O₃

[ Molecular Weight ]:
156.10000

[ Exact Mass ]:
156.02800

[ PSA ]:
121.96000

[ Index of Refraction ]:
1.861