NPD8733

Names

[ Name ]:
NPD8733

[Synonym ]:
Acetamide, N-[2-(4-methoxybenzoyl)-3-benzofuranyl]-
N-[2-(4-Methoxybenzoyl)-1-benzofuran-3-yl]acetamide

Biological Activity

[Description]:

NPD8733 (NPD-8733) is a small-molecule ligand of valosin-containing protein (VCP)/p97, binds to the D1 domain of VCP/p97; suppresses the enhanced migration of NIH3T3 cells co-cultured with MCF7 cells using a wound healing co-culture assay.

[References]

References 1. Suvarna K, et al. J Biol Chem. 2019 Jan 4. pii: jbc.RA118.004741. View Related Products by Target p97/VCP

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
567.0±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₈H₁₅NO₄

[ Molecular Weight ]:
309.316

[ Flash Point ]:
296.7±28.7 °C

[ Exact Mass ]:
309.100098

[ LogP ]:
3.30

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.641