1-(2-FURYL)-2-NITROETHYLENE

Names

[ CAS No. ]:
699-18-3

[ Name ]:
1-(2-FURYL)-2-NITROETHYLENE

[Synonym ]:
2-(2-Nitrovinyl)furan
1-(2-furyl)-2-nitroethene
FURAN,2-(2-NITROVINYL)
(E)-2-(2-nitrovinyl)furan
(2-furyl)-2-nitroethylene
MFCD00030600
Ethylene,1-(2-furyl)-2-nitro
F2189-0206
2-Furylnitroethylene
2-(2-furyl)-1-nitroethylene
1-(2-Furyl)-2-nitroethylene
1-(furan-2-yl)-2-nitroethylene
2-((1E)-2-nitrovinyl)furan
2-(2-furyl)-1-nitroethene

Chemical & Physical Properties

[ Density]:
1.270±0.06 g/cm3(Predicted)

[ Boiling Point ]:
222.7±15.0 °C(Predicted)

[ Melting Point ]:
72-75 °C(lit.)

[ Molecular Formula ]:
C₆H₅NO₃

[ Molecular Weight ]:
139.10900

[ Exact Mass ]:
139.02700

[ PSA ]:
58.96000

[ LogP ]:
2.05020

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LU3325000

CHEMICAL NAME :: Furan, 2-(2-nitrovinyl)-

CAS REGISTRY NUMBER :: 699-18-3

LAST UPDATED :: 199012

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C6-H5-N-O3

MOLECULAR WEIGHT :: 139.12

WISWESSER LINE NOTATION :: T5OJ B1U1NW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,33,1953

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 305 mg/m3/10M

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NDRC** National Defense Research Committee, Office of Scientific Research and Development, Progress Report. Volume(issue)/page/year: NDCrc-132,NOV1942

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S22-S36/37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
LU3325000

[ HS Code ]:
2932190090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2932190090

[ Summary ]:
2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles

Involvement of oxidative stress in bactericidal activity of 2-(2-nitrovinyl) furan against Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus.

Microb. Pathog. 91 , 107-14, (2016)

The involvement of reactive oxygen species and oxidative stress in 2-(2-nitrovinyl) furan mediated bacterial cell death was investigated in Escherichia coli, Pseudomonas aeruginosa and Staphylococcus ...

Characterization and molecular modeling of the inclusion complexes of 2-(2-nitrovinyl) furan (G-0) with cyclodextrines. Ruz V, et al.

Int. J. Pharm. 439(1) , 275-285, (2012)

Catalyst-free Friedel-Crafts alkylation of naphthols with nitrostyrenes in the presence of water. Halimehjani AZ, et al.

Tetrahedron Lett. 50(13) , 1441-1443, (2009)