3-Iodo-L-tyrosine

Names

[ CAS No. ]:
70-78-0

[ Name ]:
3-Iodo-L-tyrosine

[Synonym ]:
3-Iodotyrosine
EINECS 200-744-8
3-IODO-L-TYROSINE
MFCD00002608
Monoiodotyrosine
3-Monoiodo-L-tyrosine
Tyrosine, 3-iodo-, L-
Tyrosine, 3-iodo-
H-Tyr(3-I)-OH

Biological Activity

[Description]:

H-Tyr(3-I)-OH is an effective tyrosine hydroxylase inhibitor.

[Related Catalog]:

Natural Products >> Acids and Aldehydes

Research Areas >> Others

[Target]

Human Endogenous Metabolite

[In Vitro]

H-Tyr(3-I)-OH (3-iodo-L-tyrosine) is as effective inhibitor of tyrosine hydroxylase. At a concentration of 100μM 3-iodo-L-tyrosine inhibits the enzymatic activity 100% and at a concentration of 10μM it inhibits 60-70%[1].

[References]

[1]. GOLDSTEIN M, et al. INHIBITION OF TYROSINE HYDROXYLASE BY 3-IODO-L-TYROSINE. Life Sci (1962). 1965 Jan;4:261-4.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.9±0.1 g/cm3

[ Boiling Point ]:
391.0±42.0 °C at 760 mmHg

[ Melting Point ]:
210 °C (dec.)(lit.)

[ Molecular Formula ]:
C₉H₁₀INO₃

[ Molecular Weight ]:
307.085

[ Flash Point ]:
190.3±27.9 °C

[ Exact Mass ]:
306.970520

[ PSA ]:
83.55000

[ LogP ]:
1.54

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.689

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
dilute aqueous acid: soluble

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922509090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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