Phenoxyacetyl chloride

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
226.3±13.0 °C at 760 mmHg

[ Melting Point ]:
28 - 30ºC

[ Molecular Formula ]:
C₈H₇ClO₂

[ Molecular Weight ]:
170.593

[ Flash Point ]:
108.3±0.0 °C

[ Exact Mass ]:
170.013458

[ PSA ]:
26.30000

[ LogP ]:
2.07

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.525

[ Storage condition ]:
Store at RT.

Click to get detail MSDS

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314-H335

[ Supplemental HS ]:
Reacts violently with water.

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R14;R34;R36/37

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
29189090

Click to get detail synthetic route

Precursor

DownStream

[ HS Code ]: 29189090

Penicillin V acylase from Pectobacterium atrosepticum exhibits high specific activity and unique kinetics.

Int. J. Biol. Macromol. 79 , 1-7, (2015)

Penicillin V acylases (PVAs, E.C.3.5.11) belong to the Ntn hydrolase super family of enzymes that catalyze the deacylation of the side chain from phenoxymethyl penicillin (penicillin V). Penicillin ac...

Preparation and properties of 5-phenylphenoxymethylpenicillin.

J. Med. Chem. 18(5) , 486-90, (1975)

Cycloaddition of azidoacetyl chloride to benzyl D-5,5-dimethyl-5-phenyl-2-thiazoline-4-carboxylate (1a) gave 5-phenyl-6alpha-azidopenicillanate (2a). By catalytic reduction of 2a and reaction with phe...

Transient silylation of the guanosine O6 and amino groups facilitates N-acylation.

Org. Lett. 6(15) , 2555-7, (2004)

[reaction: see text] The formation of a guanosine derivative silylated at both the O6 and amino groups was identified by (15)N NMR. This intermediate allows facile reaction with acetyl chloride or phe...

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